Local Antibiotic Therapy in Osteomyelitis

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Local antibiotic therapy in osteomyelitis.

The local delivery of antibiotics in the treatment of osteomyelitis has been used safely and effectively for decades. Multiple methods of drug delivery have been developed for the purposes of both infection treatment and prophylaxis. The mainstay of treatment in this application over the past 20 years has been non-biodegradable polymethylmethacrylate, which has the advantages of excellent eluti...

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Antibiotic therapy of chronic post-traumatic osteomyelitis.

Many therapeutic approaches to the management of chronic post-traumatic osteomyelitis have been proposed and studied (Neuber 1896, Blanke 1952, Bischofberger 1953, Kosinzew 1954, Ruhl 1954, Nikitin 1955, Endler 1957, Lerch 1957, Bikfalvi and Ecke 1960, Th#{246}rmer 1960, Wynn 1960, Axhausen 1961 , Compere 1962, Farber 1962, Murray 1962, Willenegger 1963, Dahmen 1965). The condition, because of ...

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Systemic antibiotic therapy for chronic osteomyelitis in adults.

The standard recommendation for treating chronic osteomyelitis is 6 weeks of parenteral antibiotic therapy. However, oral antibiotics are available that achieve adequate levels in bone, and there are now more published studies of oral than parenteral antibiotic therapy for patients with chronic osteomyelitis. Oral and parenteral therapies achieve similar cure rates; however, oral therapy avoids...

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Local antibiotic therapy in rectal cancer surgery.

UNLABELLED Infectious complications and their consequences are still key issues in rectal cancer surgery. Currently, intravenous antibiotic administration is a recognized method for lowering the rate of these complications. The aim of the study was to assess the efficacy of complementary application of a gentamicin-impregnated sponge in the perineal wound or in the vicinity of intestinal anasto...

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Local application of free antibiotic powder in the treatment of osteomyelitis in a rat model.

To date, several strategies have been developed to provide local antibiotic therapy in the treatment of osteomyelitis, such as antibiotic-loaded bone cement, antibiotic-impregnated collagen sponges, polymethylmethacrylate beads, antibiotic-loaded bone graft, antibiotic-loaded synthetic bone substitutes, and antibiotic-coated implants. The optimum carrier for local antibiotic therapy has not bee...

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ژورنال

عنوان ژورنال: Seminars in Plastic Surgery

سال: 2009

ISSN: 1535-2188,1536-0067

DOI: 10.1055/s-0029-1214162